Copper regulation refers to the mechanisms by which cells and organisms maintain proper levels of copper within their systems. Copper is an essential nutrient that plays a critical role in various biological processes, such as energy production, antioxidant defense, and connective tissue formation. However, excessive or insufficient levels of copper can be harmful to cells and organisms. Research in copper regulation aims to understand the complex pathways involved in copper uptake, distribution, storage, and excretion in cells and organisms. This includes studying the various proteins and enzymes that are involved in these processes, as well as the regulatory mechanisms that control copper homeostasis. Overall, the study of copper regulation is important for understanding how disturbances in copper metabolism can lead to various diseases, such as Wilson's disease, Menkes disease, and Alzheimer's disease. It also has implications for developing new therapeutic approaches for treating these disorders and for improving the nutritional quality of crops through biofortification.